Jose Ignacio Gomez

DC1 – RNF10 signaling pathway in physiology and Alzheimer Disease-induced mitochondrial dysfunction

José Ignacio Gómez Blanco received his MSc degree in Neuroscience from the Universidad Autónoma de Madrid. Currently, he is pursuing a PhD at the Università degli Studi di Milano under the supervision of Professors Elena Marcello and Monica Di Luca. In his doctoral studies, he is dedicated to Project 1, which aims to unravel the RNF10 signaling pathway in physiology and Alzheimer’s Disease-induced mitochondrial dysfunction.

Alexandre Carrea

DC2 – Identification of memory tasks-activated metabolic pathways in wild-type and Alzheimer disease​

Alexandre Carrea obtained his MSc degree in Medical Biology from the University of Lausanne. For his contribution to the Eternity project, he will be working under the supervision of Professors Diego Scheggia and Nico Mitro on Project 2. His role will be to study the different metabolic pathways acquired and maintained during episodic memory in a mouse model. He will also assess the effect of different diets on these metabolic pathways and memory.

meral celikag

DC3 – Investigating the neuronal function of the novel regulator of mitochondria Zinc Finger CCCH-Type Containing 10 (Zc3h10)​

Meral Celikag received an MSc degree in Dementia: Causes, Treatments, and Research from University College London. She is currently a PhD student under the supervision of Professors Nico Mitro and Elena Marcello at the Università degli Studi di Milano. Here, she will be working on Project 3, investigating the neuronal function of the novel mitochondrial regulator Zc3h10.

Giulia Cutugno

DC4 – Role of bioenergetic pathways in the microglial inflammatory response to an obesogenic diet​

Giulia Cutugno received a Single Cycle degree in Pharmacy from the University of Milan. She is currently a PhD student at the University of Bordeaux, under the supervision of Dr. Agnès Nadjar. Here, she will work on Project 4, with the aim of studying bioenergetic alterations induced in hypothalamic microglia by an obesogenic diet and the consequences of these microglial changes on hypothalamic neural networks.

Evangelia Kyriakidou

DC5 – Role of mTOR pathway in the metabolic response of microglia in a mouse model of obesity​​

Evangelia Kyriakidou earned her MSc in the field of Neurosciences at the National and Kapodistrian University of Athens. She is currently a PhD student in the field of neuroimmunology and obesity under the supervision of Dr. Agnès Nadjar at the University of Bordeaux, Neurocentre Magendie, France. Here, she will be working on Project 5 with the aim of deciphering the role of the mTOR pathway in the metabolic response of microglia under an obesogenic diet.

Maëlle Habert

DC6 – Mitochondrial bioenergetics in microglia differentiation and upon metabolic insults during aging

Maëlle Habert completed her MSc in Integrative Biology and Physiology at Sorbonne University, specializing in neurodegenerative diseases through the International Master in Neurodegenerative Diseases program. Currently, a PhD student at DZNE Bonn, Germany, under the supervision of Dr. Daniele Bano and Dr. Melania Capasso, her research on Project 6 will investigate the role of mitochondrial bioenergetics in microglia differentiation and its response to metabolic insults throughout the aging process.

Clement Torrent

DC7 – How brain mitochondria bioenergetics affect the inflammatory phenotype of aged microglia

Clement Torrent received MSc degrees in Neurosciences and in Human Nutrition and Health from the University of Poitiers and the University of Bordeaux, respectively. He is currently a PhD student in neuroimmunology under the supervision of Dr. Melania Capasso and Dr. Daniele Bano at DZNE Bonn, Germany. Here, he will be working on Project 7 with the aim of better understanding how the bioenergetics of brain mitochondria affect the inflammatory phenotype of aged microglia.

Davide Passaro

DC8 – Isocaloric twice-a-day diet and brain
mitochondria during aging

Davide Passaro obtained his MSc degree in Cognitive Neuroscience from the University of Rome, where he worked on astrocytic metabolism in genetic diseases. He is now a PhD student at the Neuroenergetics and Metabolism Lab at the University of Salamanca, where he is supervised by Professors Juan Pedro Bolaños and Ángeles Almeida. Here, he will be working on Project 8, which aims to assess how fatty acid consumption changes mitochondrial efficiency and autophagy of brain cells in aged mice.

Thomas Zanettin

DC9 – Isocaloric twice-a-day diet in learning
and memory during aging.​​

Thomas Zanettin earned an MSc in Pharmaceutical Biotechnology, Pharmacogenomics, and Precision Therapeutics at the University of Milan. He is presently a Ph.D. student in neuroscience under the direction of Professors Juan Pedro Bolaños and Ángeles Almeida at the University of Salamanca, Spain. There, he will be working on Project 9, aimed at understanding how an isocaloric twice-a-day (ITAD) diet affects memory and learning during aging in mice.

Sarah Morsy

DC10 – Chimeric antigen receptor T (CAR-T) cells to target aging, neurodegeneration and senescence

Sarah Morsy earned her MSc in Molecular Biology as part of the interuniversity program between KU Leuven, the University of Antwerp and Vrije Universiteit Brussel. She is currently a PhD student under the supervision of Dr. Armin Ehninger and Dr. Dan Ehninger at AVENCELL. Here, she is working on Project 10 aiming at the development and validation of a chimeric antigen receptor T (CAR-T)-cell-based approach to tackle cellular senescence, aging, and age-associated pathology.

Questions and contacts

For further information please contact us

eternity@unimi.it

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